中华皮肤科杂志 ›› 2019, Vol. 52 ›› Issue (9): 593-597.doi: 10.3760/cma.j.issn.0412-4030.2019.09.001
李春英 李舒丽
收稿日期:
2018-09-04
修回日期:
2019-03-24
出版日期:
2019-09-15
发布日期:
2019-08-30
通讯作者:
李春英
E-mail:lichying@fmmu.edu.cn
基金资助:
Li Chunying, Li Shuli
Received:
2018-09-04
Revised:
2019-03-24
Online:
2019-09-15
Published:
2019-08-30
Contact:
Li Chunying
E-mail:lichying@fmmu.edu.cn
Supported by:
摘要: 【摘要】 目前关于白癜风的发病机制研究除了以往备受关注的黑素细胞内在缺陷和T细胞介导的靶向黑素细胞的特异性免疫应答外,越来越多的研究关注黑素细胞内在损伤激活的固有免疫反应,以及角质形成细胞在白癜风皮肤免疫微环境中的关键调控作用。但仍有较多问题尚未解决,包括黑素细胞如何激活固有免疫、进而启动适应性免疫应答,以及角质形成细胞如何与T细胞交流调控皮肤免疫等。未来我们需要明确以上各方面如何协同促进白癜风黑素细胞损伤,进而开发针对性的治疗措施和药物。
李春英 李舒丽. 白癜风发病机制研究热点解析[J]. 中华皮肤科杂志, 2019, 52(9): 593-597.doi:10.3760/cma.j.issn.0412-4030.2019.09.001
Li Chunying, Li Shuli. Pathogenesis of vitiligo[J]. Chinese Journal of Dermatology, 2019, 52(9): 593-597.doi:10.3760/cma.j.issn.0412-4030.2019.09.001
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