玫瑰痤疮发生的免疫学研究进展

中华皮肤科杂志 ›› 2017, Vol. 50 ›› Issue (3): 219-221.

玫瑰痤疮发生的免疫学研究进展

王岚琦,鞠强

上海市交通大学医学院附属仁济医院皮肤科

收稿日期:2016-12-14 修回日期:2017-01-12 发布日期:2017-03-01
通讯作者: 鞠强 E-mail:qiangju401@sina.com
基金资助:
糖皮质激素调节CCL20在银屑病加重过程中的机理探讨

Immunological pathogenesis of rosacea

Lan-Qi WANG¹,

Received:2016-12-14 Revised:2017-01-12 Published:2017-03-01

摘要/Abstract

摘要： 玫瑰痤疮是一种常见的累及面部的慢性炎症性皮肤病，临床表现为面中部突出区短暂红斑或持续性红斑（3个月以上）、丘疹、脓疱及血管扩张，皮疹有明显散发于口周倾向。常见的临床分型为红斑毛细血管扩张型（erythematotelan?giectatic rosacea，ETR），丘疹脓疱型（papulopustular rosacea，PPR），肥大增生型（phymatous rosacea，PhR）和眼型（ocular）［1］。导致玫瑰痤疮的病因及发病机制尚未完全明了，内源性因素如遗传背景、皮肤屏障功能破坏、神经血管失调及免疫失衡等参与疾病的发生发展；此外，环境因素也与玫瑰痤疮密切相关，已知明确的诱发因素有紫外线、酒精、辛辣刺激、冷热、表皮毛囊蠕螨等。在内外因素共同作用下，围绕皮肤血管发生免疫及炎症反应是玫瑰痤疮发生的主线［2］……

王岚琦鞠强. 玫瑰痤疮发生的免疫学研究进展[J]. 中华皮肤科杂志, 2017,50(3):219-221. doi:

Lan-Qi WANG. Immunological pathogenesis of rosacea[J]. Chinese Journal of Dermatology, 2017, 50(3): 219-221.doi:

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