萎缩型隆突性皮肤纤维肉瘤二例

中华皮肤科杂志 ›› 2011, Vol. 44 ›› Issue (7): 465-467.

萎缩型隆突性皮肤纤维肉瘤二例

陈浩¹,薛燕宁¹,²,王焱¹,佘晓东¹,姜祎群¹,曾学思¹,孙建方¹

1. 南京中国医学科学院北京协和医学院皮肤病研究所
2. 江苏省中医院皮肤科

收稿日期:2010-09-07 修回日期:2010-09-23 出版日期:2011-07-15 发布日期:2011-07-12
通讯作者: 孙建方 E-mail:fangmin5758@yahoo.com.cn

Atrophic dermatofibrosarcoma protuberans: 2 case report

², Yi-Qun JIANG²,

Received:2010-09-07 Revised:2010-09-23 Online:2011-07-15 Published:2011-07-12

摘要/Abstract

摘要：

报道2例萎缩型隆突性皮肤纤维肉瘤。患者分别为16岁和24岁的男性，临床最初均表现为界限清楚的萎缩型红斑，逐渐在红斑基础上发生结节。病程分别为6年和5年。皮损组织病理检查显示表皮萎缩或正常，肿瘤细胞在真皮浅层呈波浪状排列，平行于表皮；肿瘤细胞在真皮下部呈席纹状、车幅状、编织状排列，并可见肿瘤细胞侵犯皮下脂肪，分割脂肪细胞。肿瘤细胞表达波形蛋白、CD34，不表达CD68和S100蛋白。

关键词: CD34

Abstract:

Two cases of atrophic dermatofibrosarcoma protuberans （DFSP） are reported. The patients were a 16-year-old and a 24-year-old boy with a clinical course of 6 and 5 years respectively. The lesions began as well-marginated atrophic erythema, and subcutaneous nodules appeared gradually on the erythema. Histopathology showed atrophic or normal epidermis, wavy arrangement of tumor （spindle） cells in the superficial dermis which was aligned parallel to the epidermis, storiform arrangement of tumor cells in the lower dermis, and typical lacelike pattern of infiltration of subcutaneous fat tissue with tumor cells. Immunohistochemistry showed that the tumor cells stained positive for vimentin and CD34, but negative for S100 or CD 68.

Key words: CD34

陈浩薛燕宁王焱佘晓东姜祎群曾学思孙建方. 萎缩型隆突性皮肤纤维肉瘤二例[J]. 中华皮肤科杂志, 2011, 44(7): 465-467.

Yi-Qun JIANG. Atrophic dermatofibrosarcoma protuberans: 2 case report[J]. Chinese Journal of Dermatology, 2011, 44(7): 465-467.

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