中华皮肤科杂志 ›› 2011, Vol. 44 ›› Issue (6): 451-452.

• 药物与临床 • 上一篇    下一篇

复方氟米松软膏多中心、随机、自身对照治疗湿疹皮炎的临床研究

刘栋华1,梁伶2,严煜林3,温斯建4,5,林有坤6,李德宪7,陈德华4,肖文8   

  1. 1. 广西医科大学第一附属医院皮肤科
    2. 南宁广西医科大学附属第一医院皮肤科
    3. 南宁市广西医科大学第一附属医院皮肤科
    4.
    5. 广西医科大学第一附属医院皮肤性病科
    6. 广西医科大学第一附属医院
    7. 桂林医学院附属南溪山医院皮肤科
    8. 柳州市广西医科大学第四临床医学院皮肤科
  • 收稿日期:2010-10-26 修回日期:2010-12-01 出版日期:2011-06-15 发布日期:2011-06-02
  • 通讯作者: 梁伶 E-mail:gxmull@163.com

Compound flumetasone ointment in the treatment of eczema and dermatitis: a multicenter, randomized and self-controlled clinical study

  • Received:2010-10-26 Revised:2010-12-01 Online:2011-06-15 Published:2011-06-02

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摘要：

目的 探讨缩短复方氟米松软膏外用时间对治疗湿疹皮炎疗效的影响。方法 采用多中心、随机、自身对照的方法，将入选的392例患者分为复方氟米松软膏常规用药组、用药1小时和用药2小时组，三组患者均治疗2周后评价疗效。结果 三组患者治疗2周后症状、体征总积分均显著下降（P<0.05）。三组间相互比较，积分下降值和临床有效率无显著差异（P>0.05）。结论 外用复方氟米松软膏治疗湿疹皮炎，可以缩短药物作用时间至1~2小时以减轻或消除油腻不适感而疗效不降低。

关键词: 软膏

Abstract:

Objective To observe the effect of compound flumetasone ointment therapy for eczema and dermatitis by shorten the time of external use. Methods A multicenter, randomized, self-control methods were used to compare the effects of patients treated by compound flumetasone ointment, The 392 selected patients were divided into regular treatment group, treatment for 1 hour group and treatment for 2 hours group. All the patients received 2 weeks treatment and the effects were evaluated. Results The patients of three groups received 2 weeks of treatment with total score of symptoms and signs significantly decreased. Comparisons among the three groups, score decrease and clinical efficacy had no significant difference. Conclusions Topical compound flumetasone ointment in the treatment of eczema dermatitis can be shortened the time for 1 to 2 hours of external use, discomfort of greasiness may be reduced or eliminated without effect reduction.

Key words: ointment