中华皮肤科杂志 ›› 2011, Vol. 44 ›› Issue (2): 137-138.

• 短篇论著 • 上一篇    下一篇

石膏样小孢子菌引起体癣二例及病原学研究

刘伟1,陈伟2,王爱平1,万喆1,李若瑜1   

  1. 1. 北京大学第一医院皮肤科
    2.
  • 收稿日期:2010-06-09 修回日期:2010-08-14 出版日期:2011-02-15 发布日期:2011-02-10
  • 通讯作者: 刘伟 E-mail:liuw90@yahoo.com
  • 基金资助:

    国家自然科学基金;北京市自然科学基金

Two cases of tinea caused by Microsporum gyeum and their pathogenic analysis

  • Received:2010-06-09 Revised:2010-08-14 Online:2011-02-15 Published:2011-02-10

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摘要：

2例患儿以皮疹伴瘙痒就诊，均有宠物接触史，自行外用糖皮质激素类药物等均无效。真菌直接镜检可以见到皮屑中有链状孢子或菌丝，皮屑培养为石膏样小孢子菌，2菌株对酮康唑、咪康唑、联苯苄唑、特比萘芬、伏立康唑敏感。经口服特比萘芬和外用环吡酮胺进行治疗痊愈。

关键词: 药物敏感性

Abstract:

Two patients were admitted to the hospital for 2-month history of pruritic eruptions on the forehead and 2-week history of pruritic eruptions on the leg, respectively. Both patients had a history of pet contact. Topical application of glucocorticoids did not work well. Dermatological examination revealed a patch measuring 5 cm × 6 cm on the forehead of one patient and a patch measuring 2 cm × 3 cm on the leg of the other patient. Both patches were surrounded by red papules and scaling. Microscopic examination of skin scales revealed hyphae and chain-like spores, and culture of skin scales grew Microsporum gyeum. Both the isolates of Microsporum gyeum were sensitive to ketoconazole, miconazole, bifonazole, terbinafine, and voriconazole. Both patients were healed after treatment with oral terbinafine and topical ciclopirox olamine.

Key words: antifungal susceptibility testing