中华皮肤科杂志 ›› 2011, Vol. 44 ›› Issue (11): 815-817.

• 研究报道 • 上一篇    下一篇

三种胎盘制剂联合红外线照射治疗儿童白癜风的临床疗效观察

王涛1,许爱娥2,尉晓冬1,董东1   

  1. 1. 杭州市第三人民医院
    2. 安徽医科大学附属杭州市第三人民医院皮肤科
  • 收稿日期:2011-01-14 修回日期:2011-03-10 出版日期:2011-11-15 发布日期:2011-11-01
  • 通讯作者: 许爱娥 E-mail:xuaiehz@msn.com
  • 基金资助:

    杭州市科技局项目

Evaluation of clinical efficacy of three different placental preparations in the treatment of childhood vitiligo

  • Received:2011-01-14 Revised:2011-03-10 Online:2011-11-15 Published:2011-11-01

摘要:

目的 探讨3种胎盘制剂治疗儿童白癜风的临床疗效。方法 儿童白癜风182例,分为3组,分别采用黑素生成素、人胎盘组织液以及人胎盘脂多糖3种药物外用,3组均联合红外线照射,每天照射2次,每次20 min,照射期间每隔5 min搽药液1次。结果 黑素生成素治疗组治疗儿童白癜风有效率为75.65%;人胎盘组织液组有效率35.00%;人胎盘脂多糖组有效率44.44%,3种胎盘制剂的总有效率之间差异有统计学意义(P值均 < 0.05),尤其是对于头皮较大面积患者,黑素生成素组疗效明显优于其他两组。结论 3种胎盘制剂外用联合红外线照射治疗儿童白癜风有较好疗效。

关键词: 黑素生成素 人胎盘组织液 人胎盘脂多糖 儿童 白癜风 治疗

Abstract:

Objective To evaluate the clinical efficacy of three different placental preparations in the treatment of childhood vitiligo. Methods Eighty-two children with vitiligo were divided into 3 groups to be topically treated with melagenine, human placental tissue fluid and human placental lipopolysaccharide respectively. All the patients were additionally treated with infrared rays for 20 minutes twice daily. The drugs were topically applied with an interval of 5 minutes during the irradiation. Results The response rate was 75.65%, 35.00% and 44.44% respectively in the melagenine-, human placental tissue fluid- and human placental lipopolysaccharide-treated patients, and significant differences were observed between the three groups of patients (all P < 0.05). In particular, melagenine was superior to the other two preparations for the treatment of large areas of vitiligo on the scalp. Conclusion The 3 placental preparations combined with infrared irradiation show favorable efficacy for the treatment of childhood vitiligo.