Abstract: Objective To update the knowledge of contact allergy to topical corticosteroids. Methods A total of 1,822 patients, who suffered from inflammatory skin disorders but did not respond well to topical corticosteroids, were enrolled into this study. Patch test was performed on these subjects with corticosteroid allergens, following the standardized procedures recommended by the International Contact Dermatitis Research Group （ICDRG）. Results Of all patients, 78（4.28%） had positive patch test. Among the 78 patients, 33 were males, 45 females, and most were young or middle-aged. During 96-168 hours after the removal of patches, positive results were observed in 42.31% （33/78） of the patients. Twenty eight patients had anaphylactic reaction induced by hydrocortisone butyrate, 25 by dexamethasone sodium phosphate, and 17 by triamcinolone acetonide. A correlation between sensitizing glucocorticoids detected by patch testing and administrated drugs in clinic was found in 74 cases. Conclusions Contact allergy caused by topical corticosteroids is not rare, and more attention should be paid to this issue in the treatment of inflammatory skin disorders.