中华皮肤科杂志

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浆细胞性女阴炎一例

吴黎明, 李学熹, 李凌, 陈洵礼, 项晶晶, 俞小虹   

  1. 杭州市第一人民医院皮肤科, 310006
  • 收稿日期:2007-02-26 出版日期:2007-10-15 发布日期:2007-10-15

A case of plasma cell vulvitis

WU Li-ming, LI Xue-xi, LI Ling, CHEN Xun-li, XIANG Jing-jing, YU Xiao-hong   

  1. Department of Dermatology, Hangzhou First People's Hospital, Hangzhou 310006, China
  • Received:2007-02-26 Online:2007-10-15 Published:2007-10-15

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摘要： 报告1例浆细胞性女阴炎。患者女,60岁,反复外阴红斑、糜烂9个月,复发伴加重1个月。双侧大小阴唇上方可见暗红斑,表面潮湿,散在白色伪膜样糜烂面,阴蒂弥漫性增生肥大。皮损病理示真皮上中部弥漫性炎症细胞浸润,大部分为成熟浆细胞,并可见少量红细胞外溢。临床表现及病理特点符合浆细胞性女阴炎。本病治疗困难,复方倍他米松注射液和α-干扰素皮损内注射取得近期疗效。

关键词: 浆细胞, 外阴炎, 女性

Abstract: A case of plasma cell vulvitis is reported.A 60-year-old woman patient presented with recurrent erythema and erosion in the vulva for 9 months.She complained of an recurrence and aggravation of the lesions for 1 month.Physical examination revealed dusky-red macules with moist surface,scattered white pseudomembrane-like erosion on both labias,and extensive hypertrophy of the clitoris.Histologic examination showed that there was a diffuse infiltration with inflammatory cells in upper to middle dermis, most of which were mature plasma cells,and a few extravasating erythrocytes.The clinical manifestations and pathological findings supported the diagnosis of plasma cell vulvitis,which was recalcitrant to treatment. Repeated intralesional injections ofbetamethasone complex solution(diprospan)and interferon alpha resulted in short-term improvement of the disease.

Key words: Plasma cells, Vulvitis, Female