UVA1光疗法在部分皮肤病中的应用现状

中华皮肤科杂志 ›› 2004, Vol. 37 ›› Issue (4): 247-250.

UVA1光疗法在部分皮肤病中的应用现状

王丽英, 常宝珠, 郑家润

中国医学科学院、中国协和医科大学皮肤病研究所南京 210042

收稿日期:2003-07-03 出版日期:2004-04-15 发布日期:2004-04-15

Received:2003-07-03 Online:2004-04-15 Published:2004-04-15

摘要/Abstract

摘要： 长波紫外线1(UVA1,波长340～400nm)光疗法是1992年开始应用于皮肤科临床的一种较新的光疗法.与传统的长波紫外线补骨酯素(PUVA)以及中波紫外线(UVB)光疗法相比,UVA1不仅具备深穿透性,而且无补骨酯素相关不良反应和光毒反应.皮肤科学者已在多种以往应用传统PUVA和(或)UVB疗法的皮肤疾患中进行了UVA1疗效的大量临床研究,结果显示UVA1光疗法对特应性皮炎、硬斑病、蕈样肉芽肿等多种皮肤T细胞介导的疾病有效.其作用机制仍不明确,可能与其对^[1]人体皮肤的免疫调节效应,以及表皮和(或)真皮细胞群功能的改变有关.

王丽英, 常宝珠, 郑家润. UVA1光疗法在部分皮肤病中的应用现状[J]. 中华皮肤科杂志, 2004, 37(4): 247-250.

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