中华皮肤科杂志 ›› 2004, Vol. 37 ›› Issue (1): 22-24.

• 论著 • 上一篇    下一篇

系统性红斑狼疮患者器官/系统损伤的评价

满孝勇, 李学平, 郑经芬, 周晓鸿, 郭云, 冒长峙   

  1. 昆明医学院第二附属医院皮肤科, 泰安271000
  • 收稿日期:2002-12-11 出版日期:2004-01-15 发布日期:2004-01-15
  • 基金资助:
    中华医学会皮肤科分会基金(2002-32)

The Evaluation of Organ Damage in Systemic Lupus Erythematosus

MAN Xiao-yong, LI Xue-ping, ZHENG Jing-fen, ZHOU Xiao-hong, GUO Yun, MAO Chang-zhi   

  1. Department of Dermatology, the Second Affiliated Hospital, Kunming Medical College, Kunming 650101, China
  • Received:2002-12-11 Online:2004-01-15 Published:2004-01-15

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摘要： 目的 研究系统性红斑狼疮(SLE)患者器官/系统损伤的情况。方法 以SLE损伤指数(SDI)评价121例女性和15例男性SLE患者器官/系统的损伤情况。统计学分析采用SPSS软件包。结果 SLE患者SDI最小值为0分,最大值9分,平均(1.79±2.22)分。损伤最多的器官是肾脏(39.0%),其次为肌肉骨骼系统(19.9%)和心血管系统(18.4%)。预后和生活环境及病程(10年以下和10年以上)不同,SLE患者SDI值比较差异具有显著性(P<0.05),而不同性别患者SDI值比较差异无显著性(P>0.05)。发病年龄、诊断年龄与SDI值进行相关分析,没有发现其相关性。结论 SDI是一有效测定SLE损伤的工具,为更好地判断SLE患者的预后提供了理论依据。

关键词: 红斑狼疮,系统性, 评价

Abstract: Objective To study the organ damage in patients with systemic lupus erythematosus (SLE) and its significance in prognosis. Methods The SLE damage index (SDI) was used to evaluate 121 female and 15 male patients. Results Among these patients, the lowest and the highest SDI was 0 or 9, separately (average: 1.79±2.22). Most damaged organ was renal (39.0%), followed by muscle/skeletal system (19.9%) and cardiovascular system (18.4%). There was statistically significant difference of SDI in different groups of prognosis, life condition or disease duration (< 10 and > 10 years). However, there was no significant difference of SDI in different sex groups. The correlation analysis revealed that the age at onset or diagnosis was not related to SDI. Conclusion SDI is effective in evaluating the organ damage in predicting prognosis of SLE patients.

Key words: Lupus erythematosus, systemic, Evaluation