中华皮肤科杂志 ›› 1998, Vol. 31 ›› Issue (5): 273-275.

• 论著 •    下一篇

国内首见球毛壳菌所致暗色丝孢霉病

王家俊1, 章强强1, 李莉1, 冯文莉2   

  1. 1. 上海华山医院皮肤科真菌室, 200040;
    2. 山西医科大学第二附属医院
  • 收稿日期:1998-01-06 修回日期:1998-04-20 出版日期:1998-10-15 发布日期:1998-10-15

Phaeohyphomycosis Caused by Chaetomium Globosum: First Case Report in China

Wang Jiajun1, Zhang Qiangqiang1, Li Li1   

  1. Department of Dermatology, Huashan Hostpital, Shanghai Medical University, Shanghai 200040
  • Received:1998-01-06 Revised:1998-04-20 Online:1998-10-15 Published:1998-10-15

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摘要： 报告一例由球毛壳菌所致的皮肤和甲暗色丝孢霉病。患者男性,13岁,江苏农民。主诉面部、四肢、掌跖、臀部出现暗红色结节、斑块伴溃疡和结蛎壳样厚痂5年。组织病理显示为慢性肉芽肿样反应,见大量淡棕色分枝分隔的菌丝。损害中分离出的真菌25℃和37℃生长良好。菌落灰褐色,有大量棕黑色子囊壳。根据子囊壳、顶生附属丝、侧生附属丝和子囊孢子形态学特点本菌被定为球毛壳菌。

关键词: 球毛壳菌, 暗色丝孢霉病, 甲真菌病

Abstract: A 13-year-old male farmer suffered from cutaneous and nail phaeohyphomycosis for five years is reported in this paper. The lesions were dull red, nodules and well-defined plaques with ulcerations, mainly on the face, extremities, palmar and plantar surfaces and buttocks. Some of them were covered with thick greyish-black crusts. General examination did not reveal abnormal findings except the skin lesions. Histopathology showed granulomatous response with numerous light brown septate branching hyphae. The colonies were greyish-brown on SDA and PDA at 25℃ and 37℃ with brownish-black ascomata. The ioslated strain was identified as Chaetomium globosum based on the morphological features of ascomata, ascomal hairs and ascospores.

Key words: Chaetomium globosum, Phaeohyphomycosis, Onychomycosis