中华皮肤科杂志 ›› 1997, Vol. 30 ›› Issue (6): 380-382.

• 论著 • 上一篇    下一篇

结节性硬化症20例分析

孙新芬, 方丽   

  1. 上海医科大学附属华山医院皮肤科 200040
  • 收稿日期:1997-02-19 修回日期:1997-05-30 出版日期:1997-12-15 发布日期:1997-12-15

Analysis of 20 Patients with Tuberous Sclerosis

Sun Xinfen, Fang Li   

  1. Institute of Dermatology, Shanghai Medical University, Shanghai 200040
  • Received:1997-02-19 Revised:1997-05-30 Online:1997-12-15 Published:1997-12-15

摘要: 为了熟悉结节性硬化症的特征性皮肤表现和常见的皮肤以外病变,早期正确诊断本病并及早发现重要内脏器官的病变,对20例结节性硬化症患者进行了体检、头颅CT、腹部B超、胸部X线、手足X线及眼科检查.结果发现结节性硬化症常累及皮肤、脑、肾等器官,色素减退斑是最常见、最早的皮肤表现,易误诊;头颅CT检查对本病的诊断有很大的价值.建议临床医师应对色素减退斑尤其伴有癫痫的患者提高警惕,并注意结节性硬化症患者内脏病变的检查和随访.

关键词: 结节性硬化症

Abstract: In order to familiar the characteristic cutaneous manifestation and common extracutaneous involvement of tuberous sclerosis(TS), which faciliate the clinicians to diagnose correctly and detect important visceral involvement earlier, 20 patients with TS were studied, including physical and dermatological examination, cranial CT, abdominal ultrasonography, chest X-ray, hand and foot X-ray and ophthalmological examination. The results showed that skin, brain and kidneys were involved frequently in TS patients. The hypomelanotic macules were the most common and earliest in the cutaneous lesions and often led to misdiagnosis. Cranial CT was of great value in the diagnosis of TS. The authors recommend that clinicians have to pay attention to the hypomelanotic macules in the patients especially with epilepsy. The involvement of visceral organs should also be examined and followed up in TS patients.

Key words: Tuberous sclerosis