中华皮肤科杂志 ›› 1997, Vol. 30 ›› Issue (5): 310-311.

• 论著 • 上一篇    下一篇

东北刺人参挥发油抗真菌实验及临床研究

付爱华1, 张宏桂2, 张林1, 刘松艳2, 吴广宣2   

  1. 1. 白求恩医科大学第一临床学院皮肤科 长春 130021;
    2. 基础医学院普化教研室
  • 收稿日期:1996-11-04 修回日期:1997-03-17 出版日期:1997-10-15 发布日期:1997-10-15
  • 基金资助:
    吉林省卫生厅科研基金

Clinical and Laboratory Studies of the Essential Oil from Oplopanax Elatus Nakai Against Fungi

Fu Aihua1, Zhang Honggui2, Zhang Ling1   

  1. Department of Dermatology, First Hospital of Norman Bethune Medical University, Changchun 130021
  • Received:1996-11-04 Revised:1997-03-17 Online:1997-10-15 Published:1997-10-15

PDF

480

赞

摘要： 东北刺人参是主要分布于中国东北的药用植物.为充分利用长白山丰富资源,研制天然抗真菌新药,采用试管内药基法,对东北刺人参挥发油进行抗真菌实验研究.结果:它有很强的抗真菌活性,对常见皮肤癣菌有抑菌和杀菌作用,MIC为0.0625%～0.125%,MFC为0.125%～0.25%.用1%刺人参挥发油配制的霜剂对皮肤无刺激性,治疗皮肤癣菌病有效率达90%,值得今后进一步研究.

关键词: 东北刺人参, 挥发油, 皮肤癣菌, 皮肤癣菌病

Abstract: Oplopanax elatus Nakai,a medicinal plant,is mainly distributed in Northeast China.In order to make use of abundant resources of Chang Bai Shan,to make researches on natural anti fungal medicinal preparations,we studied the essential oil from Oplopanax elatus Nakai against fungi in vitro,the results showed that there was a marked antimycotic action of the essential oil.The MIC against common pathogenic dermatophytes ranged from 0.0625-0.125% and MFC 0.125-0.25%.1% cream of the essential oil was applied to the patients with dermatomycoses,the rate of effectiveness was 90%.This antifungal agent is purely natural,and shows no stimulation to the skin.

Key words: Oplopanax elatus nakai, Essential oil, Dermatophytes, Dermatomycoses