中华皮肤科杂志 ›› 1996, Vol. 29 ›› Issue (1): 18-21.

• 论著 • 上一篇    下一篇

43例季节性接触性皮炎皮肤试验研究

庄丽华, 赵辨   

  1. 南京医科大学第一附属医院皮肤科, 210029
  • 收稿日期:1995-03-13 修回日期:1995-09-29 出版日期:1996-02-15 发布日期:1996-02-15
  • 基金资助:
    国家自然科学基金

Study on Skin Tests of 43 Patients with Seasonal Contact Dermatitis

Zhuang Lihua, Zhao Bian   

  1. Department of Dermatology, The First Affiliated Hospital, Nanjing Medical University, Nanjing 210029
  • Received:1995-03-13 Revised:1995-09-29 Online:1996-02-15 Published:1996-02-15

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摘要： 为探索季节性接触性皮炎病因及发病机理.我们对43例季节性接触性皮炎(季节组)患者进行花粉抗原斑贴试验等一系列皮肤试验研究,并设62例变态反应性接触性皮炎(非季节组)及50例健康组为对照。结果,季节组血清总IgE水平及阳性率、花粉抗原特异性IgE阳性率、花粉点刺及斑试阳性率均明显高于非季节组及健康组,特异性IgE与花粉抗原点刺及斑试反应间均有明显的相关性和较高的符合率。表明季节性接触性皮炎发病与花粉抗原诱导的IgE介导的迟缓相反应有关。

关键词: 花粉抗原, 皮炎,接触性, 免疫球蛋白类

Abstract: To study the etiology and pathogenesis of seasonal contact dermatitis (SG),some skin tests including pollen allergen patch test were performed in 43 cases of SG.Sixty-two patients with al-lergic contact dermatitis(NSG) and 50 healthy individual(HG) were used as control.The results showed that the level and positivity rate of total serum IgE in SG,and the positivity rate of specific IgE,pollen allergen prick test and patch test in SG were higher than those in NSG and HG.The speeific IgE,pollen allergen prick test and pollen allergen patch test were significantly correlated,and showed high consistency.These results indieate that the pathogenesis of seasonal contact dermatitis he obviously associated with pollen allergen-induced IgE-mediated late-phase reaction.

Key words: Pollen allergens, Dermatitis,contact, Immunoglobulins