中华皮肤科杂志 ›› 1995, Vol. 28 ›› Issue (5): 284-286.

• 论著 • 上一篇    下一篇

结缔组织增生性恶性黑素瘤

范钦和1, Allen PW2   

  1. 1. 江苏省人民医院羰理科, 南京 210029;
    2. 澳大利亚南澳洲伊丽莎白女皇医院病理科
  • 收稿日期:1995-02-09 修回日期:1995-04-22 出版日期:1995-10-15 发布日期:1995-10-15

Desmoplastic Malignant Melanoma

Fan Qinhe1, Allen PW2   

  1. 1. Department of Pathology, Jiangsu Province Hospital, Nanjing 210029;
    2. The Queen Elizabeth Hospital, SA 5011, Australia
  • Received:1995-02-09 Revised:1995-04-22 Online:1995-10-15 Published:1995-10-15

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摘要： 结缔组织增生性恶性黑素瘤是近年来提出的一种较少见的肿瘤.现报告58例,其特点为肿瘤细胞呈梭形,肉瘤样,背景富含胶原.部分病例见到亲神经现象,表皮内可见恶性雀斑样痣或发育不良痣中所见的异型黑素细胞,真皮常见日光照射变化.绝大部分病例S100蛋白强阳性.预后与普通恶性黑素瘤相似,为高度恶性.

关键词: 恶性黑素瘤

Abstract: A clinical,histologic and immunohistochemical review of 58 cases of desmoplastic malignant melanoma is reported.The lesion presented sarcoma-like cells with a rich collagen background. Neurotropism could be seen around the nerve,Hutchinson melanotic freckle or dysplastic nevi at theepidermis,and solar-damage in the dermis in some cases.S100 protein was strongly positive in most of thepatients.The prognosis of this disease was not better than that of usual malignant melanoma.

Key words: Malignant melanoma