中华皮肤科杂志 ›› 1995, Vol. 28 ›› Issue (1): 8-10.

• 论著 • 上一篇    下一篇

皮肤恶性T细胞性淋巴瘤伴反应性噬血组织细胞增生症的临床病理研究

周青, 徐天蓉   

  1. 江苏省人民医院病理科 南京 210029
  • 收稿日期:1994-02-23 修回日期:1994-06-20 出版日期:1995-02-15 发布日期:1995-02-15

T-cell Lymphoma Associated with Reactive Histiocytic Hyperplasia with Hemophagocytosis

Zhou Qin, Xu Tiangrong   

  1. Department of Pathology, Jiangsu Province People's Hospital, Nanjing 210029
  • Received:1994-02-23 Revised:1994-06-20 Online:1995-02-15 Published:1995-02-15

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摘要： 报道6例皮肤T细胞性恶性淋巴瘤伴噬血组织细胞增生症.病变局限于真皮和皮下脂肪组织,灶性的肿瘤性T淋巴细胞浸润和分化良好的噬血组织细胞增生伴各种炎症细胞浸润.4例表现为病情进行性恶化、复发或死亡.并探讨其发病机理、诊断标准及鉴别诊断.

关键词: 皮肤T细胞淋巴瘤, 组织细胞增生症

Abstract: Six cases of T-cell lyrnphoma associated with reactive histiocytic hyperplasia with hemophagocytosis (HHH) localized primarily to the skin and subcutaneous fat were described.Initial biopsy findings may he misinterpreted as benign panniculitis.Four of which were progressive,recurrent,even fatal (follow-up for 8-36 months).Histologically the lesions of all cases were composed of a mixture of small and medium sized atypical lymphoid cells and benign hemophagocytes infiltrated with neutrophils and eosinophils between fat cells.The mechanism and differential diagnosis of the disease were discussed.

Key words: Cutaneous T-cell lymphoma, Histiocytic hyperplasia