中华皮肤科杂志 ›› 1992, Vol. 25 ›› Issue (1): 16-18.

• 论著 • 上一篇    下一篇

MAC387抗原在炎性皮肤病及皮肤肿瘤中角朊细胞的表达

邹铭西   

  1. 中日友好医院皮肤科, 北京 100029
  • 收稿日期:1990-09-03 修回日期:1990-12-27 出版日期:1992-02-15 发布日期:1992-02-15

Keratinocyte Expression of MAC387 Antigen in Inflammatory Cutaneous Disease and Skip Tumors

ZOU Ming-Xi   

  1. China-Japan Friendskip Hospital, Beijing, 100029
  • Received:1990-09-03 Revised:1990-12-27 Online:1992-02-15 Published:1992-02-15

摘要: 研究了MAC387及抗γ干扰素单克隆抗体在几种炎性皮肤病及皮肤肿瘤中角脱细胞的染色.结果在大部分病例中角脱细胞表达MAC387抗原,而无γ干扰素抗原;在正常皮肤组织两者都不表达.结果提示人的角朊细胞可能具有辅助细胞的功能,在皮肤免疫反应中起着重要作用.本实验不能说明γ干扰素有诱导MAC387抗原表达的能力.

关键词: 抗体, 单克隆, 角阮细胞

Abstract: MAC387 and interferon-γ(IFIV-γ)monoclonal antibodies staining human keratinocytes in inflammatory cutaneous disease (ICD) and skin tumors (ST) were studied. Keratinocytes were positive for MAC387 antigen in great majority of cases, while keratinocytes were negative for IFN- γ antigen in most cases.

Key words: Antibodies, monoconal, Keratinocytes