中华皮肤科杂志 ›› 1991, Vol. 24 ›› Issue (5): 301-303.

• 论著 • 上一篇    下一篇

应用S100蛋白观察各型麻风皮损内皮神经的改变

刘子君, 梁智   

  1. 中山医科大学病理教研室, 广州 510089
  • 收稿日期:1990-03-12 修回日期:1990-09-08 出版日期:1991-10-15 发布日期:1991-10-15

Study of Dermal Nerves in Various Types of Leprosy by S 100 Protein Immunoperoxidase Technique

LIU Zi-Jun, LIANG Zhi   

  1. Sun Yat-Sen Uniaersity of Medical Science, Guangzhou
  • Received:1990-03-12 Revised:1990-09-08 Online:1991-10-15 Published:1991-10-15

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摘要： 应用S100蛋白显示50例各型麻风皮损病灶内皮神经的变化,观察到皮神经改变有松散、肿胀及变形、断裂与崩解.TT及BT病灶内皮神经数目较LL,BL及BB明显减少,是与其皮神经断裂及崩解较明显有关.本文尚发现麻风菌及胶质对S100蛋白呈阳性反应.并认为此法对麻风病变的诊断有意义.

Abstract: Skin biopsies of 50 caste from various types of leprosy were studied by S100 protein immunohistoclremical technoque.The results indicated that not only Scbwann cells of dermal nerves,but also Myca.Leprae and gloea reaoted positively with S100 protein.