中华皮肤科杂志 ›› 1989, Vol. 22 ›› Issue (6): 392-394.

• 论著 • 上一篇    下一篇

急性皮肤刺激试验组织学检查与肉眼观察的比较

方家麟, 刘季和, 孙慧珍, 刘景忠, 郁宏志, 顾克显   

  1. 中国医学科学院皮肤病研究所
  • 收稿日期:1988-05-16 修回日期:1988-09-14 出版日期:1989-12-15 发布日期:1989-12-15

ACUTE SKIN IRRITATION TEST IN ANIMALS-A COMFARiSON BETWEEN THE HISTOLOGICAL EXAMINATION AND MACROSCOPICAL EVALUATION

FANG Jia-Lin, LIU Ji-He   

  1. Institute of Dermadology, Chinese Academy of Medacal Sciences, Nanjing
  • Received:1988-05-16 Revised:1988-09-14 Online:1989-12-15 Published:1989-12-15

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摘要： 作者应用动物斑贴试验方法将新制订的组织学评分法与肉眼观察皮肤刺激反应评分相比较,发现二者之间呈正相关关系,认为组织学评分标准是可以采用的,这一结果也为拟定病理组织学刺激强度评价标准提供依据.

Abstract: Using the animal patch test,the authors compared the histoiogical scoring with the visual assessment described by Draize,and found that there was a positive correlation between the two different methods,and considered-W at the histological scoring might be used,wand ehc present results also piovided a basis for ftrrmuIating the histological criteria in the assessment of intensity of irritation.