中华皮肤科杂志 ›› 1989, Vol. 22 ›› Issue (4): 239-240.

• 论著 • 上一篇    下一篇

间接核酸杂交方法检测尖锐湿疣寻常疣组织中DNA相关序列

姜国调1, 谷淑燕2, Wolf H3   

  1. 1. 北京协和医院;
    2. 中国预防医学科学院病毒学研究所;
    3. Pehenkofer Institute Munich, West Germany
  • 收稿日期:1988-02-01 修回日期:1988-07-04 出版日期:1989-08-15 发布日期:1989-08-15

Detection of papillomavirus DNA by indirect hybridization in biopsies from patients with genital warts and verruca vulgaris

JIANG Guo-Tiao1, GU Shu-Yan2   

  1. Beijing Union Medical College Hospital
  • Received:1988-02-01 Revised:1988-07-04 Online:1989-08-15 Published:1989-08-15

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摘要： 本文采用间接核酸杂交的方法检测33例尖锐湿疣和34例寻常疣活检组织中的人类乳头瘤病毒(HPV)1,2,4,6,10,11,16和18型DNA相关序列.结果表明:25例尖锐湿疣HPV10、11,16和18型DNA阳性,阳性率75.76%;8例HPV6阳性,阳性率24.24%.2例寻常庞HPV1阳性,阳性率5.88%;32例HPV2阳性,阳性率94.11%.

Abstract: HPV1, 2, 4, 6, 10, 11, 16, 18 DNA was detected in biopsies from 33 patients with genital warts and 34 patients with verruca vulgaris by indirect nucleus acid hybridization. The result showed that 25 out of 33 patients with genital warts were positive for HPV 10,11 16, 18 DNA and other 8 cases for HPV 6 DNA, and 32 out of 34 patients with verruca vulgaris were positive for HPV 2 DNA and other 2 cases for HPV 1 DNA.