中华皮肤科杂志 ›› 1988, Vol. 21 ›› Issue (3): 135-138.

• 论著 • 上一篇    下一篇

用体视学方法定量研究郎格罕细胞形态

谢勇1, 周鼎耀1, 郑茂荣1, 赵慧娟2   

  1. 1. 第二军医大学附属长海医院皮肤科;
    2. 第二军医大学附属长海医院病理科
  • 收稿日期:1987-03-05 修回日期:1987-05-26 出版日期:1988-06-15 发布日期:1988-06-15

QUANTITATIVE MORPHOLOGICAL STUDY OF LANGERHANS CELLS BY STEREOLOGICAL METHOD

Xie Yong1, Zhou Dingyao1   

  1. Changhai Hospital, Shanghai
  • Received:1987-03-05 Revised:1987-05-26 Online:1988-06-15 Published:1988-06-15

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摘要： 运用计算机图象分析技术对ATP酶染色的正常及局部氮芥处理后的豚鼠表皮LC进行了形态定量分析,发现正常LC胞质和胞核的周长均与其面积的平方根呈非常显著的正相关和直线回归关系,为从形态上识别LC建立了理论依据.直接测量和推导出的几何参数还反映出用药后LC的胞质肿胀、液化,树突减小和细胞核增大等在电镜下不易直接观察到的形态结构的变化.实验结果表明形态定量分析是LC的客观、精细和实用的研究方法.

Abstract: Quantitative morphological study of ATPase stained normal and topically nitrogen mustard treated LCs in guinea pig epidermis was perfcrmed by computerised image analysis technique. It was found that there was a very significant correlation and linear regression between perimeter and the square root of its area for both cytoplasm and nucleus. This evidence prmvides a theoretical basis for morphological identification of LCs.