中华皮肤科杂志 ›› 1988, Vol. 21 ›› Issue (2): 84-87.

• 论著 • 上一篇    下一篇

102例足癣患者免疫学研究

郭宁如1, 吕桂霞1, 梅亚宁1, 李安生1, 沈永年1, 石沁2, 陈祥生1, 吴绍熙1   

  1. 1. 中国医学科学院皮肤病研究所;
    2. 铁道部南京浦镇车辆厂医院
  • 收稿日期:1986-12-08 修回日期:1987-09-03 出版日期:1988-04-15 发布日期:1988-04-15

IMMUNOLOGICAL STUDY ON 102 CASES OF TINEA PEDIS

Guo Ningru1, LüGuixia1   

  1. Institute of Dermatology, Chines Aecademy of Medical Sciences, Nanjing
  • Received:1986-12-08 Revised:1987-09-03 Online:1988-04-15 Published:1988-04-15

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摘要： 本文对102例各型足癣患者进行了有关细胞免疫(LIT,LAF)、体液免疫(Ig,C3,C4)等方面的观察,以脐血50份作对照,发现患者中特异细胞免疫均为阳性,且与机体状况,如年龄、病型、合并症等有关.此外红色毛癣菌所感染的患者14/15中IgE异常增高,其意义待定.以上结果提示足癣患者存在有全身性免疫反应,而患者的免疫功能状况似与本病的易于复发有一定关系.

Abstract: The cellular(leucocytic migration inhibition test-LIT;leucocyte adherence inhibition_LAI) and humoral(Ig,C3,C4) immunological tests were carried out in 102 patients with tinea pedis,with 50 umbilical cord blood specimens as control.We found that in all patients the specific migration index_MI and non-adherence inhibition index_NAII weer positive in comparison with the umbilical cord blood.These results were related to the eondition of patients(such as age,clinical synnptoms and complications),and there were cross reactions between the two antigens(Ag.of trichophyton rubrum and Ag.of T.Gypseum).Ctn the other hand,14 out of 15 cases infected by Trirhnnhvton ruhrum appeared higher IgE level,but its relation to this disease was undeterminz.d.Thus it shows that the immunological reactions do exist in patients with tinea pedis.It seems that the immunological function of patients may have influence upon the high percentage of recurrence in this desease.