中华皮肤科杂志 ›› 1987, Vol. 20 ›› Issue (4): 211-214.

• 论著 • 上一篇    下一篇

新生儿剥脱性皮炎 新生儿期TEN的诊断与治疗探讨

苏敬泽1, 陈秋霞2, 黄唯辑2, 钱戍春3, 肖伟平4, 李成龙5   

  1. 1. 中国医学科学院皮肤病研究所;
    2. 广东湛江医学院附院皮肤科;
    3. 新疆医学院附院皮肤科;
    4. 湖北医学院一附院皮肤科;
    5. 白求恩国际和平医院皮肤科
  • 收稿日期:1986-06-10 修回日期:1986-07-25 出版日期:1987-08-15 发布日期:1987-08-15

Dermatitis exfoliativa neonatorum

Su Jingze1   

  • Received:1986-06-10 Revised:1986-07-25 Online:1987-08-15 Published:1987-08-15

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摘要： 本文报告31例新生儿剥脱性皮炎.通过临床资料,诊断性实验检查及治疗对比,分为感染型的STEN及药物型的DTEN进行分析,对本病的诊断及治疗进行了探讨.认为据临床经过、皮疹特点及细胞学检查可鉴别STEN及DTEN.本病的发病年龄及皮疹特殊,宜独立诊断为新生儿剥脱性皮炎,不应以SSSS或TEN来代替.STEN治疗主要是选用有效抗生素,原则上不主张联用皮质类固醇激素,而DTEN的治疗则首先应当早期、短程、大量使用激素.本文同时讨论了治疗中应注意的若干问题.

Abstract: This paper reported 31 cases of dermatitis extfoliativa neonatorum, which, through tomparison of clinical manifestations, laboratory investigations and results of treatment, were classified into STEN and DTEN, and the diagnosis and treatment of this disease were discussed. The authers emphasized that STEN and DTEN could be distinguished by clinical course, characteristics of skin lesions and cytologic examination. Because of its age of onset and the characteristic skin lesions, it should be diagnosed independently as neonatal exfoliative dermatitis instead of SSSS and TEN. STEN should be treated with effective antibiotics and generally corticosteroids should not be used in combination, whereas DTEN should be treated early with short course of large dose of systemic corticosteroids.