中华皮肤科杂志 ›› 1987, Vol. 20 ›› Issue (2): 92-94.

• 论著 • 上一篇    下一篇

男性SLE的临床分析及性激素水平的测定

冯树芳1, 许月林1, 富志民2, 曹佩琴2, 何根英2, 姚红霞2, 戴海丽2   

  1. 1. 上海医科大学华山医院皮肤科;
    2. 上海市第一妇婴保健院
  • 收稿日期:1986-05-24 修回日期:1986-09-02 出版日期:1987-04-15 发布日期:1987-04-15

Clinical analysis and serum sex hormones of male patients with SLE

Fend Shufang1   

  • Received:1986-05-24 Revised:1986-09-02 Online:1987-04-15 Published:1987-04-15

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摘要： 本文分析了60例男性SLE,将其病情及严重度与60例女性SLE作对照观察,发现两组病人的病情及严重度相似,但男性病人的盘状损害和神经精神系统累及更多.60例男病人中有20例以及20例年龄上与之配对的健康男性测定了6种血清性激素:E2,T,P,FSH,LH和PRL.结果表明男性SLE的E:增高,T降低和E2/T比值显著增高,E2和E2/T值与SLE的严重度有正相关关系.

Abstract: A comparison of manifestations and severity of SLE in 60 male patients and female controls was studied. The results showed that the manifestations and the severity of SLE tended to be similar between the two groups, but discoid lesions and neuropsychiatric involvement were more common in the males. Serum sex hormone profiles were performed on 20 of the above 60 male patients and 20 age-matched healthy male volunteers. The profile consisted of estradiol (E2), testosterone (T), progesterone, follicular stimulating hormone, luteiaizing hormone, and prolactin. An increase in serum EQ, decrease in serum T and marked increase in ratio of E2 to T. E2 values and E2/T ratio in the males correlated sienificantlv with severitv of the disease.