中华皮肤科杂志 ›› 1986, Vol. 19 ›› Issue (6): 327-329.

• 论著 • 上一篇    下一篇

皮肌炎的血清肌红蛋白检测

许德清1, 杨秀强1, 郭秀筠2   

  1. 1. 中山医科大学孙逸仙纪念医院皮肤科;
    2. 中山医科大学孙逸仙纪念医院检验科
  • 收稿日期:1986-01-03 修回日期:1986-04-06 发布日期:1986-12-15

Determinations of myoglobin in sera of patients with dermatomyositis

Xu Deqing1   

  • Received:1986-01-03 Revised:1986-04-06 Published:1986-12-15

摘要: 本文报告采用放射免疫测定法,对28例皮肌炎患者作了39次血清肌红蛋白(Mb)检测,16次的Mb值在50ng/ml以上,占41.0%,以活动期患者计算则占48.5%.其敏感度优于GPT及LDH的检测,且不低于24小时尿肌酸及GOT,因此可做为皮肌炎的辅助诊断参考.

Abstract: This article presents the results of 39 determinations of myoglobin (Mb) with radioim-munoassays in sera from 28 patients with dermatomyositis. Positive results for Mb(> 50ng/ml) were found in 16 sera (41.0%). In the active cases the percentage of positive results was even higher (48.5%). We found the Mb radioimmunoassay to be more sensitive than the SGPT and LIiH determination, and its sensitivity not lower than the 24 hour urine creatine and SGOT determination, run concurrently on these sera. This suggests that Mb radioimmunoassay may be valuable as an adjunct,in the diagnosis of dermatomyositis.