中华皮肤科杂志 ›› 1986, Vol. 19 ›› Issue (4): 205-206.

• 论著 • 上一篇    下一篇

天疱疮皮损组织的扫描电镜观察

郭莹1, 孙国文1, 宋芳吉1, 杨次颖1, 杨景春2   

  1. 1. 中国医科大学附属一院皮肤科;
    2. 指导者
  • 收稿日期:1985-08-12 修回日期:1985-11-09 出版日期:1986-08-15 发布日期:1986-08-15

Observation on the skin lesions of pemphigus by SEM

Guo Ying1   

  • Received:1985-08-12 Revised:1985-11-09 Online:1986-08-15 Published:1986-08-15

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摘要： 本文报告了5例天疱疮病人皮损组织的扫描电镜观察,病变棘细胞间隙增大,细胞棘状突起及绒毛减少,使表面光滑,细胞呈球形或纺锤形.认为是天疱疮自身抗体引起超微结构的改变,最终导致棘松解.

Abstract: The paper reports the observation on the skin lesions from 5 patients with pemphigus by SEM. Under SEM, it was observed that the intercellular spaces between acantholytic cells enlarged, the prickles and villi on the cell surface decreased, the cells became smooth and spherical or spindle in shape. It was thought that the pemphigus autoantibodies caused the ultrastructural changes and led to acantholysis.