中华皮肤科杂志 ›› 1986, Vol. 19 ›› Issue (4): 195-196.

• 论著 • 上一篇    下一篇

用改良滤膜法检测银屑病多形核白细胞的趋化性

王经珊, 韩安林, 郑亚萍   

  1. 济南军区总医院皮肤科
  • 收稿日期:1985-10-25 修回日期:1986-03-27 出版日期:1986-08-15 发布日期:1986-08-15

Assessment of neutrophil chemotaxis in psoriasis using improved filter membrane method

Wang Jingshan   

  • Received:1985-10-25 Revised:1986-03-27 Online:1986-08-15 Published:1986-08-15

PDF (PC)

185

赞

摘要： 应用上海产微孔滤膜,代替国外产微孔滤器,以直通玻璃管和华氏管为上下室,建立的PMN趋化性滤膜测定法,是一种体外测定PMN趋化性的可行方法.该法装置简而易行,操作简便,用血量少.105例银屑病患者和30例正常人对照组测定结果表明,银屑病PMN趋化性与病程分期有关,进行期银屑病患者趋化性显著增高,退行期和服乙双吗啉两组则与正常对照无差异.

Abstract: Neutrophil (PMN) chemotaxis in patients with psoriasis vulgaris was assessed using in vitro improved filter membrane technique.The micro-pore filter menbrane used was made in Shanghai, China. Adventages of this method were simple and convenient, and require a small amount of blood. 105 patients with psoriasis and 30 healthy control subjects were studied. The results obtained from both groups suggested that the PMN chemotaxis was related to the stage of psoriasis, increased significantly in patients in the progressive stage, and no significant difference in patients in the regressive stage and patients treated with Bi molant (AT-1727).