中华皮肤科杂志 ›› 1986, Vol. 19 ›› Issue (3): 152-154.

• 论著 • 上一篇    下一篇

银屑病患者血清和尿液中RNase的观察

谭昇顺1, 韦永光1, 王惠民1, 孙国英2, 李广元2, 王志贵2, 李伯壎3   

  1. 1. 西安医科大学第二附属医院皮肤科;
    2. 西安医科大学第二附属医院中心化验室;
    3. 西安医科大学第二附属医院指导者
  • 收稿日期:1985-09-05 修回日期:1985-11-27 出版日期:1986-06-15 发布日期:1986-06-15

Observation on serum and urine ribonuclease activity in patients with psoriasis

Tan Shengshun1   

  • Received:1985-09-05 Revised:1985-11-27 Online:1986-06-15 Published:1986-06-15

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摘要： 本文报告对101例处于不同病程分期的银屑病患者血清和尿液中碱性核糖核酸酶活力进行了测定.结果均明显高于正常人(p<0.001),进行期>静止期>消退期(P<0.05-0.001).作者认为这种酶活力与病变消长一致的变化,可能对阐明银屑病的发病机理、治疗方法的选择和预后的判定有一定价值.

Abstract: Serum and urine alkaline ribonuclease activity detected in 101 patients with psoriasis in different stages of illness is reported in this article. The results showed that the alkaline ribonuclease activity unit(RALT) in patients with psoriasis were markedly higher than that of normal control group(P<0.001),with RAU in progressive stzge > RAU in stationary stage}RAU in resolving stage (P<0.05-0.001).The authors consider tliat the change of serum and urine RNase activity in parallel with the stage of skin lesions might have a cerlain value in explaining the pathogenesis,selecting the therapeutic method,and judging the prognosis of psoriasis.