中华皮肤科杂志 ›› 1986, Vol. 19 ›› Issue (2): 74-77.

• 论著 • 上一篇    下一篇

100例各型天疱疮的追踪观察

靳培英, 李慧珠, 戴星   

  1. 中国医学科学院皮肤病研究所皮研室
  • 收稿日期:1985-08-16 修回日期:1985-10-31 出版日期:1986-04-15 发布日期:1986-04-15

Follow-up observation of 100 cases of pemphigus

Jin Peiying   

  • Received:1985-08-16 Revised:1985-10-31 Online:1986-04-15 Published:1986-04-15

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摘要： 本文通过门诊随访与信访,在1985年4月至8月,追踪观察了1964~1985年间的100例各类天疱疮患者,对其病程与转归进行了分析,发现死于天疙疮本病与皮质类固醇激素治疗的合并症者13例,其死亡率为13%,明显低于过去.本研究指出,大多数死亡病例,主要是由于治疗不规则,自动停药,当病情复发后,必须提高皮质类固醇的用量,从而引起副反应以及致命的合并症而死亡.本文也对开始即以皮质类固醇加免疫抑制剂联合治疗方案的疗效,给予初步的肯定.因其可以减少两药用量,缩短病程,对减少死亡率是有利的.

Abstract: One hundred patients with various types of pemphigus were folluweel up using questionaires and examined at the out-patients department of this institute, and the course and outcome of these patients were analysed. The total mortality of varioas types of pemphigus was 13% during the period from 1964-1985, which was much lower than that in the past. This study indicated that most patients died from improper therapy, including irregular zdministration and withdrawal of drugs without the permission of physician. When the recurrence of the disease took place the dosage of prednisone had to be increased, this in turn led the patients to die of severe complications.