中华皮肤科杂志 ›› 1985, Vol. 18 ›› Issue (3): 150-152.

• 论著 • 上一篇    下一篇

银屑病患者的红细胞免疫功能(附100例分析)

夏应魁1, 门永继1, 刘汉绂1, 曾玉明2, 张正侯2, 韩绍哲2, 刘玥2   

  1. 1. 中国医科大学附二、三院皮肤科;
    2. 中国医科大学附二、三院检验科
  • 收稿日期:1984-07-24 修回日期:1984-10-11 出版日期:1985-09-15 发布日期:1985-09-15

lmmunologic function of red blood cell in the patients with psoriasis：An analysis of 100 cases

Xia Yingkui1   

  • Received:1984-07-24 Revised:1984-10-11 Online:1985-09-15 Published:1985-09-15

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摘要： 本文以白色念珠菌为标记物,进行红细胞两种免疫粘附(RCIA)花环试验和血循环免疫复合物(CIC)测定,对132例健康人和100例银屑病患者的红细胞免疫功能状态进行了统计分析.结果显示,银屑病患者的两种RCIA花环形成率、CIC均锌正常人明显增高,P<0.05型、期之间.男女之间无显著差异,P>0.05.病程10年以上组的两种RCIA花环形成率均高于10年以下组.治疗有效病例,疗后红细胞两种花环形成率皆明显下降.文章结合银屑病讨论了当前对红细胞参与免疫作用的初步认识,提出RCIA花环率可望作为疾病预后判断的客观指标之一.

Abstract: Two forms of red cell immunoadherence (RCIA) rosette test and circulating immune complex determination were carried out with Candida albicans as a marker in 100 patients with psoriasis and 132 normal persons.The results showed that the rate of positive result in the two forms of RCIA test and circulating immune complex determination were apparently greater than those in the control group. There was no apparent difference among the various forms and stages of the disease and variation in sex (P>0.05).The results of the two forms of RCIA test in the patients with a course of the disease over 10 years were greater than those with their course below 10 years. After an effective therapy, there was an apparent fall in the rate of positive result in the two forms of rosette formation test. In this paper, the mediation of RBC in the immunologic function in association with psoriasis was discussed. It is suggested that RCIA could be used as an objective criterion for the prognosis of psoriasis.