中华皮肤科杂志 ›› 1984, Vol. 17 ›› Issue (3): 188-190.

• 论著 • 上一篇    下一篇

组织样麻风瘤透射电镜及扫描电镜的进一步观察

刘季和1, 李文忠1, 杨理合1, 孔庆英1, 夏明玉2, 朱文元2, 黄立2   

  1. 1. 中国医学科学院皮肤病研究所;
    2. 南京医学院
  • 出版日期:1984-09-15 发布日期:1984-09-15

Further observation on histoid leproma by TEM and SEM

Liu Jihe1   

  • Online:1984-09-15 Published:1984-09-15

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摘要： 本文对5例发生于不同情况(类型、时期及耐药与否)的HL结合临床及组织学所见进行孑透射电镜的观察,并对其中2例作了扫描电镜观察.结果:细胞成分与前次观察相似,可分为4种形态的巨噬细胞(即普通型、梭形、上皮样及泡沫化).但疹龄在半年以内者.比较典型,以梭形巨噬细胞为主,细胞增生明显,麻风杆菌也以实体型杆菌为多.有些菌体出现分裂象,因此推测HL的发生似与早期损害中迅速繁殖的麻风杆菌有密切关系.然而此种典型表现仅能保持一定时期.1年以上病损在光镜及电镜下病变即不典型,出现大量破碎菌体与泡沫化巨噬细胞.溶酶体内也见破碎菌.细胞增生现象亦不明显.出现此种现象的本质进行了讨论,但尚待深入探讨.

Abstract: In this article,5 cases of histoid leproma(HL) occurred in different conditions of leprosy were studied by TEM in connection with clinical manifestation and histopathological picture.Two of them were examined by SEM.The results were as follows:The cellular components of HL were similar to those being described formerly,including 4 of macrophages(i.e.ordinary,fusiform,epithelioid types and foamy macrophages).