中华皮肤科杂志 ›› 1984, Vol. 17 ›› Issue (2): 88-90.

• 论著 • 上一篇    下一篇

6例银屑病电镜观察

李景华, 张福洲, 刑新华, 王经珊   

  1. 济南部队总医院
  • 出版日期:1984-06-15 发布日期:1984-06-15

Observation on 6 cases of psoriasis by electron microscopy

Li Jinghua   

  • Online:1984-06-15 Published:1984-06-15

摘要: 选择6例不同期型银屑病患者的皮损行电镜观察,其中3例做了治疗前后对照.,例做了非皮疹区的观察.结果:表皮各层细胞均有异常,细胞之间桥粒减少.间隙加宽.棘细胞间隙有嗜中性粒细胞及淋巴细胞浸润.治愈后个别棘细胞核仍大.细胞间隙轻度增宽.非皮疹区棘细胞内线粒体聚集,细胞间隙增宽.以上表明银屑病表皮细胞发育不良,病变广泛.临床治愈病例棘细胞未能恢复正常.可能是复发的原因之一故治愈标准不能单从临床判定.

Abstract: Skin lesions from 6 patients with psoriasis in different stages were studied with EM. The lesions Taken before and after treatment in three cases and the uninvolved skin in two cases were observed. Results: Epidermal cells of different layers showed abnormal changes, The number df intercellular desmosomes diminished, and intercellular spaces widened, There was.inflammatory infiltration of neutrophils and lymphocytes in the intercellular spaces of prikle cells, Individual nuclei of prikle cells remained larger and intercellular space slightly wider after clearing of the lesions clinically, In the uninvolved areas. mitochondria were found aggregated within prikle cells and the intercellular spaces widened.