中华皮肤科杂志 ›› 1983, Vol. 16 ›› Issue (4): 216-217.

• 论著 • 上一篇    下一篇

银屑病患者Tγ细胞检查及其意义的初步探讨

李风岐1, 顾富祥1, 杨曼里1, 齐文玲1, 沈伟侠2, 杨军2, 杨文彬2   

  1. 1. 南京市鼓楼医院;
    2. 南京市医学科学研究所
  • 出版日期:1983-12-15 发布日期:1983-12-15

Preliminary investigation of Tγ cell in psoriasis and its significance

Li Fengqi1   

  • Online:1983-12-15 Published:1983-12-15

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摘要： 本文应用Fc受体法检查了62例银屑病患者的Tγ细胞.与正常人对照组比较,均非常显著降低.其中32例患者于治疗后30~60天进行了复查,与治疗前比洗显效患者Tγ细胞明显增高.无效患者仍显著低下.结果表明:Tγ细胞的升高或降低与银屑病患者的皮损消退和恶化有充可能反映了患里彗的细胞免疫功能状态.因而测定Tγ细胞对于观察银屑病的治疗效果及预后可能具有一定的临床意义.

Abstract: In this article Tγ cells of 62 patients with psoriasis before: treatment and 100 healthy controls were investigated by means of a rosette method for the Fc fragment of human IgG receptor-bearing Hymphocytes. The mean percentage of Tγ cells of the patient group wes significantly lower than. that of control group, After 30-60 days of treatment, 32 of 62 cases were tested again, Tγ cells of 20 markedly improved cases increased.obviously, wliile 12, cases with poor response were still in lower level,The results showed that increasing or decreasing of Tγ cells were related with improving or exacerbating of the disease. There fore it might reflect the cellular immunological state in the patients with psoriasis. The authors consider that the determination of Tγ cells seems to be of clinical significance especially in judgement of the therapeutic effect and the prognosis of the diseage,