中华皮肤科杂志 ›› 1983, Vol. 16 ›› Issue (2): 109-111.

• 论著 • 上一篇    下一篇

系统性红斑狼疮的缺血性骨坏死

宦秉喻, 廖志学, 许贤明   

  1. 重庆市第一人民医院
  • 出版日期:1983-06-15 发布日期:1983-06-15

Ischemic bone necrosis in systemic lupus erythematosus

Huan Bingyu   

  • Online:1983-06-15 Published:1983-06-15

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摘要： 本文通过25例SLE骨关节摄片结果,对INB与SLE的临床表现及激素治疗关系进行分析.25例SLE中INB的发生率为40%,发生INB的10例SLE50%兼有雷诺氏现象及血管炎.而不并有INB的SLE仅1例(6.6%)有血管炎等症状.本组结果支持Zizic等认为SLE患者中有一亚群其临床表现有雷诺氏现象,血管炎等者应高度怀疑可并发INB,10例INB服强的松平均47,4个月,平均总量为21979.7mg,15例无INB者服强的松平均30.4个月,平均总量为13555mg,看来皮质激素大剂量长期应用是导致INB的重要原因之一.但个体差异也值得注意.

Abstract: Ischemic necrosis of bone(INB) has been the major orthopedic problems in patients with systemic lupus erythematosis(SLE).A study was made of 25 cases of SLE after a follow-up period of 1 to 8 years in an attempt to assess the incidence of INB and to find out the possible etiological factors.Roentgenographic findings showed that 10 patients(40%) had evidence of INB in the weight bearing joints.All 10 patients had hip jointinvolvement and in 7 it was bilateral,The knees were involved in 3 patients.A total of 20 bones with ischemic necrosis were observed.