中华皮肤科杂志 ›› 1982, Vol. 15 ›› Issue (4): 221-222.

• 论著 • 上一篇    下一篇

利胆醇合并小剂量灰黄霉素治疗头癣的疗效观察

白义杰   

  1. 遵义医学院皮肤病学教研室真菌实验室
  • 出版日期:1982-12-15 发布日期:1982-12-15

Observation on the combined treatment of tinea capitis with livonalum and small dose of griseofulvin

Bai Yijie   

  • Online:1982-12-15 Published:1982-12-15

摘要: 利胆醇在试管内有较强的抗真菌作用.1:1000浓度能够抑制白念珠菌及黄癣菌、红色毛癣菌、石膏样毛癣菌等9种我国常见的皮肤癣菌. 利胆醇合用小剂量的灰黄霉素治疗头癣取得了较好效果.利胆醇0,2~0.4/日,灰黄霉素7.5mg/kg/日.连服20日,同时配合外用治疗.55例中53例治愈.治愈率为96.36%.而对照组仅为60.98%.两组有很显著的差异(P<0.01).

Abstract: Livonalum (phenylcholon)has relatively strong fungistatic action in vitro. The minimal inhibitory concentration of livonalum are 1:1000 for candida albicans and some dermatophytes which are often found in our country. 55 patients of tinea capitis were treated with Iivonalum (0.2~0.4/daily) and small doses of griseofulvin(7.5mg/kg/daily).the curing rates being 96.36%.But that of the control group was only 60.98%,and therefore there is a significant difference between these two groups (P<0.01).