中华皮肤科杂志 ›› 1982, Vol. 15 ›› Issue (3): 157-160.

• 论著 • 上一篇    下一篇

靛玉红治疗银屑病的疗效观察及原理探讨

王梦祥1, 王怀劬1, 刘文淑1, 顾孔书2, 刘爱新2, 刘广儒2, 张广文2, 石华珍2, 刘访杰3, 罗新3   

  1. 1. 中国医学科学院分院附属医院皮肤科;
    2. 中国医学科学院分院附属医院检验科;
    3. 中国医学科学院分院附属医院中国医学科学院分院附属医院同位素室
  • 出版日期:1982-09-15 发布日期:1982-09-15

Study on the therapeutic effect and pharmacological action of indirubin in treating psoriasis

Wang Mengxiang1   

  • Online:1982-09-15 Published:1982-09-15

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摘要： 本文用靛玉红治疗62例银屑病,并用乙亚胺治疗24例银屑病作为对照.靛玉红的显效率为82.26%,乙亚胺显效串为50%,前者明显为高.主要副作用为消化系统的反应,如痢疾样大便、腹痛等,可在2-4周内自行消失.作者又测定血流速度与血流量,以及CAMP与cGMP方法探讨其治疗机理.但仍有待进一步研究.

Abstract: In this article,62 cases of psoriasis were treated with Indirubin and another 24 cases with ethylene diamifie tetieacetylimide.The effective rate of lndirubin was 82.26%,while that of ethylene diamine tetreacetylimide was 50%(P<0.025).The main side-effect was the disturbance of digestive system,such as dysentery-like feces; abdominal pain etc,which map subside within 2-4 weeks spontaneouslp.The therapeutical mechanism of Indirubin was investigated preliminarily by determination of velocity and amount of blood flow and that of cAMP and cGMP,but further study should be made.