中华皮肤科杂志 ›› 1981, Vol. 14 ›› Issue (2): 67-69.

• 论著 • 上一篇    下一篇

国产益康哩治疗皮肤癣菌病357例临床疗效分析

李宇宁1, 黄文明1, 吴志华1, 苏敬泽1, 黄维辑1, 彭一平1, 张继红1, 王宗锐2, 赵永铿3   

  1. 1. 湛江医学院皮肤病学教研组;
    2. 湛江医学院皮药理学教研组;
    3. 暨南大学医学院
  • 出版日期:1981-06-15 发布日期:1981-06-15

A Clinical Analysis in Effectivertess on 357 Cases of Dermatomycoses Treated with Domestic Econazole

Li Yuning1, Huang Wenming1, Wu Zhihua1, Su Jingze1, Huang Weiji1, Peng Yiping1, Zhang Jihong1, Wang Zongrui2, Zhao Yongkeng3   

  1. 1. Department of Dermatology, Zhangjiang Medical College;
    2. Department of Dermatology, Medical College of Jinan University
  • Online:1981-06-15 Published:1981-06-15

摘要: 益康唑(Econazole)是化学合成的广谱抗真菌新药①.1969年由瑞士西拉凯米公司(Cilag-Chemic)创制成功②.化学名为1-(2-(2.4-二氯苯基)-2-(4-氯苄氧基)-乙基〕咪唑硝酸盐.

Abstract: 357 cases of dermatomycoses were treated with 1% Econazole cream.323 cases(90.6%).were cured.Recurrences took place in 27 out of the 323 cured patients(8.4%).I,n such cases,good results were obtained when treated again with 1% Econazole cream.The side effects manifested as erythema,pruritus,vesicle; erosion and scaling were found in 9%.In a doubleblind study comparing 1% Econazole cream with 1% clotrimazole cream,there was-no significant difference(p>0.05).In skin test,such as photo-allergy test,no positive reaction had been seen.