中华皮肤科杂志 ›› 1981, Vol. 14 ›› Issue (2): 63-66.

• 论著 •    下一篇

益康哇(Econazole)抗真菌实验及临床疗效初步观察

黄醒亮1, 邓锦惠2, 谢彩华1, 鲁长明2   

  1. 1. 中山医学院附二院皮肤科;
    2. 中山医学院附二院皮肤科真菌室
  • 出版日期:1981-06-15 发布日期:1981-06-15

A Preliminary Study of Econazole in its Antimycotic Effect and Clinical Therapeutic Result

Huang Xinliang1, Deng Jinhui2, Xie Caihua1, Lu Changming2   

  1. 1. Department of Dermatology, 2nd Hospital of Zhongshan Medical College;
    2. Mycotic Laboratory of the Department of Dermatology, 2nd Hospital of Zhongshan Medical College
  • Online:1981-06-15 Published:1981-06-15

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摘要： 益康唑是一种新的化学合成的广谱抗真菌药物,属咪唑(lmidazole)衍化物),化学名为1-[2-(2.4-二氯苯基)-2-(4-氯芳氧基)-乙基]一咪哩硝酸盐.1-[2-(2.4-dichlorophenyl)-2-(4-Chlorobenzyloxy)-ethyl]-imidazole nifirate.系白色结晶粉末,溶于甲醇,微溶于氯仿,极难溶于水及普通有机溶剂.

Abstract: Econazole is a new chemical compound and broad-spectrum antimycotic drug being a derivative of imidazole.The present study is based on test against fungi in vitro of Econazole which was manufactured by the Guangzhou 1st Pharmaceutical Factory.These tests have shown that Econazole has a marked action,not only in bacteriostatic,but also in bactericidal sense against certain superficial and deep mycosis.