系统性红斑性狼疮患者的染色体

中华皮肤科杂志 ›› 1981, Vol. 14 ›› Issue (1): 5-9.

系统性红斑性狼疮患者的染色体

戎诚兴¹, 王瑞绵¹, 张世明¹, 高进², 孙曾拯²

1. 湖北医学院组胚教研室;
2. 武汉市第一医院皮肤科

出版日期:1981-03-15 发布日期:1981-03-15

The Chromosome of Systemic Lupus Erythematosus

Rong Chengxin¹, Wang Ruimian¹, Zhang Shiming¹, Kao Jin², Sun Cengzheng²

1. Department of Histology andEmbryology, Hubei Medical College;
2. Department of Dermatology, Wuhan 1st Hospital

Online:1981-03-15 Published:1981-03-15

摘要/Abstract

摘要： 系统性红斑性狼疮(SLE)在病人体内可产生多种自身抗体,如抗核抗体、抗细胞质抗体、抗红细胞抗休、抗淋巴细胞抗体、抗其它白细胞抗体及抗血小板抗体等,所以将本病当作自身免疫性疾病的代表.

Abstract: Venous blood from 7 female SLE patients and 5 normal females were cultivated in vitro.Each blood specimens was transferred into two containers; one served as a control and was irradiated with ultraviolet light after being cultivated for 24 hours, the other was cultivated for 72 hours without any treatment.It was found that the structural aberration rate of the lymphocyte chromosomes of the non-irradilated patient's blood specimens is 9.5 times that of the non-irradiated normal female (p<0.01),and the structural aberration rate of the lymphocyte chromosomes of the irradiated patient's specimens is 8.7 times that of the irradiated normal person (p<0.01).Whether the blood specimens were irradiated or not, no distinct difference on the structural aberration rates of the lymphocyte chromosomes was detected in the patient's specimens or the normal person.

戎诚兴, 王瑞绵, 张世明, 高进, 孙曾拯. 系统性红斑性狼疮患者的染色体[J]. 中华皮肤科杂志, 1981, 14(1): 5-9.

Rong Chengxin, Wang Ruimian, Zhang Shiming, Kao Jin, Sun Cengzheng. The Chromosome of Systemic Lupus Erythematosus[J]. Chinese Journal of Dermatology, 1981, 14(1): 5-9.