特应性皮炎中移动健康与数字生物标志物的研究进展

doi:10.35541/cjd.20260061

中华皮肤科杂志 ›› 2026, Vol. 59 ›› Issue (6): 571-577.doi: 10.35541/cjd.20260061

特应性皮炎中移动健康与数字生物标志物的研究进展

葛佳艺¹ 刘伊瑄² 周园¹ 姚煦¹

¹中国医学科学院北京协和医学院，皮肤病医院过敏与风湿免疫科，南京 210042；²南京信息工程大学人工智能学院，南京 210044
葛佳艺和刘伊瑄对本文有同等贡献

收稿日期:2026-01-28 修回日期:2026-04-19 发布日期:2026-06-05
通讯作者: 姚煦 E-mail:dryao_xu@126.com
基金资助:
中央高校基本科研业务费专项资金（3332024092）

Mobile health and digital biomarkers in atopic dermatitis

Ge Jiayi¹, Liu Yixuan², Zhou Yuan¹, Yao Xu¹

¹Department of Allergy and Rheumatology, Hospital for Skin Diseases, Institute of Dermatology, Chinese Academy of Medical Sciences ＆ Peking Union Medical College, Nanjing 210042, China; ²School of Artificial Intelligence, Nanjing University of Information Science and Technology, Nanjing 210044, China
Ge Jiayi and Liu Yixuan contributed equally to this article

Received:2026-01-28 Revised:2026-04-19 Published:2026-06-05
Contact: Yao Xu E-mail:dryao_xu@126.com
Supported by:
Fundamental Research Funds for the Central Universities（3332024092）

摘要/Abstract

摘要： 【摘要】随着移动健康技术的不断发展，数字生物标志物逐渐成为疾病监测与管理领域的重要研究方向。与传统依赖临床或实验室检测采集的生物标志物不同，数字生物标志物多来源于日常生活场景，具有连续、动态采集的特点。特应性皮炎（AD）是常见的慢性炎症性皮肤病，具有反复发作和病情波动的特点，常需频繁医疗干预。在此背景下，将数字生物标志物引入AD管理，对于实现疾病状态的长期监测，推动个体化干预策略的制定具有重要意义。本文系统综述了移动健康技术及数字生物标志物在AD领域的研究进展，重点总结了基于智能手机和可穿戴设备的相关技术在AD预防、病情监测以及远程管理和个体化治疗中的应用现状与潜力。

关键词: 皮炎, 特应性, 生物标志物, 移动健康, 可穿戴设备, 人工智能

Abstract: 【Abstract】 With the development of mobile health technologies, digital biomarkers have gradually emerged as a promising focus in disease monitoring and management. Unlike conventional biomarkers obtained through clinical examinations or laboratory testing, digital biomarkers are primarily derived from real-world settings and enable continuous, dynamic data collection. Atopic dermatitis （AD） is a common chronic inflammatory skin disease characterized by recurrent flares and fluctuating disease activity, often requiring frequent medical intervention. In this context, integrating digital biomarkers into AD management is critical for enabling long-term monitoring of the disease and facilitating the development of personalized intervention strategies. This review provides a systematic review of recent advances in mobile health technologies and digital biomarkers in AD, highlighting the current applications and potential of smartphone- and wearable device-based approaches for the prevention, monitoring, remote management, and personalized treatment of AD.

Key words: Dermatitis, atopic, Biomarkers, mHealth, Wearable devices, Artificial intelligence

葛佳艺刘伊瑄周园姚煦. 特应性皮炎中移动健康与数字生物标志物的研究进展[J]. 中华皮肤科杂志, 2026,59(6):571-577. doi:10.35541/cjd.20260061

Ge Jiayi, Liu Yixuan, Zhou Yuan, Yao Xu. Mobile health and digital biomarkers in atopic dermatitis[J]. Chinese Journal of Dermatology, 2026, 59(6): 571-577.doi:10.35541/cjd.20260061

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特应性皮炎中移动健康与数字生物标志物的研究进展

Mobile health and digital biomarkers in atopic dermatitis

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