严重皮炎、多重过敏和代谢消耗综合征患者DSG1杂合突变1例

doi:10.35541/cjd.20220893

中华皮肤科杂志 ›› 2025, e20220893.doi: 10.35541/cjd.20220893

严重皮炎、多重过敏和代谢消耗综合征患者DSG1杂合突变1例

刘妍李小红白飞英何依玹于建斌

郑州大学第一附属医院皮肤科，郑州 450052

收稿日期:2022-12-15 修回日期:2024-05-02 发布日期:2025-09-24
通讯作者: 李小红 E-mail:judylee@zzu.edu.cn

A case of heterozygous DSG1 mutation associated severe dermatitis, multiple allergies and metabolic wasting syndrome

Liu Yan, Li Xiaohong, Bai Feiying, He Yixuan, Yu Jianbin

Department of Dermatology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China

Received:2022-12-15 Revised:2024-05-02 Published:2025-09-24
Contact: Li Xiaohong E-mail:judylee@zzu.edu.cn

摘要/Abstract

摘要： 患儿男，3岁，因全身泛发红斑、脱屑3年于2017年6月就诊。患儿自出生起即出现双下肢红色丘疹，逐渐发展为全身弥漫性红斑伴脱屑。曾于外院诊断为鱼鳞病样红皮病、特应性皮炎、湿疹等，多种外用药及中草药治疗缓解后复发……

刘妍李小红白飞英何依玹于建斌. 严重皮炎、多重过敏和代谢消耗综合征患者DSG1杂合突变1例[J]. 中华皮肤科杂志, 2025,e20220893. doi:10.35541/cjd.20220893

Liu Yan, Li Xiaohong, Bai Feiying, He Yixuan, Yu Jianbin. A case of heterozygous DSG1 mutation associated severe dermatitis, multiple allergies and metabolic wasting syndrome[J]. Chinese Journal of Dermatology,2025,e20220893. doi:10.35541/cjd.20220893

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严重皮炎、多重过敏和代谢消耗综合征患者DSG1杂合突变1例

A case of heterozygous DSG1 mutation associated severe dermatitis, multiple allergies and metabolic wasting syndrome

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