英夫利西单抗联合治疗中毒性表皮坏死松解症4例

doi:10.35541/cjd.20220887

中华皮肤科杂志 ›› 2024, e20220887.doi: 10.35541/cjd.20220887

英夫利西单抗联合治疗中毒性表皮坏死松解症4例

王文明舒畅何春霞宋洪彬吴梦茵晋红中

中国医学科学院北京协和医学院北京协和医院皮肤科疑难重症及罕见病国家重点实验室国家皮肤与免疫疾病临床医学研究中心，北京 100730

收稿日期:2022-12-09 修回日期:2023-10-20 发布日期:2024-08-19
通讯作者: 晋红中 E-mail:jinhongzhong@263.net
基金资助:
中央高水平医院临床科研业务费（2022-PUMCH-A-251）；国家自然科学基金（82073450）；国家重点研发计划项目（2022YFC3601800）

Infliximab for the treatment of 4 cases of toxic epidermal necrolysis

Wang Wenming, Shu Chang, He Chunxia, Song Hongbin, Wu Mengyin, Jin Hongzhong

Department of Dermatology, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, National Clinical Research Center for Skin and Immune Diseases, Beijing 100730, China

Received:2022-12-09 Revised:2023-10-20 Published:2024-08-19
Contact: Jin Hongzhong E-mail:jinhongzhong@263.net
Supported by:
National High-level Hospital Clinical Research Funding （2022-PUMCH-A-251）; National Natural Science Foundation of China （82073450）; National Key R&D Program of China （2022YFC3601800）

摘要/Abstract

摘要： 中毒性表皮坏死松解症（toxic epidermal necrolysis，TEN）是由药物诱发的严重不良反应，以发热、皮肤广泛坏死和剥脱为特点，可危及生命。TEN的发生率为（0.40 ~ 1.45）/100万，最常见的致病药物包括抗生素、抗癫痫药物、别嘌醇和非甾体抗炎药等……

王文明舒畅何春霞宋洪彬吴梦茵晋红中. 英夫利西单抗联合治疗中毒性表皮坏死松解症4例[J]. 中华皮肤科杂志, 2024,e20220887. doi:10.35541/cjd.20220887

Wang Wenming, Shu Chang, He Chunxia, Song Hongbin, Wu Mengyin, Jin Hongzhong. Infliximab for the treatment of 4 cases of toxic epidermal necrolysis[J]. Chinese Journal of Dermatology,2024,e20220887. doi:10.35541/cjd.20220887

参考文献 10

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英夫利西单抗联合治疗中毒性表皮坏死松解症4例

Infliximab for the treatment of 4 cases of toxic epidermal necrolysis

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