[开放获取]    Iso-Kikuchi综合征2例

doi:10.35541/cjd.20220719

中华皮肤科杂志 ›› 2023, Vol. 56 ›› Issue (4): 313-315.doi: 10.35541/cjd.20220719

[开放获取] Iso-Kikuchi综合征2例

郑冰洁¹ 林晓¹ 陈佳² 钱秋芳¹

¹上海市儿童医院皮肤科上海交通大学医学院附属儿童医院，上海 200062；²上海市皮肤病医院病理科上海市同济大学附属皮肤病医院，上海 200050

收稿日期:2022-10-12 修回日期:2023-01-06 发布日期:2023-03-31
通讯作者: 钱秋芳 E-mail:qianqf@shchildren.com.cn

Iso-Kikuchi syndrome: report of two cases

Zheng Bingjie¹, Lin Xiao¹, Chen Jia², Qian Qiufang¹

¹Department of Dermatology, Children′s Hospital of Shanghai, Children′s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200062, China; ²Department of Dermatopathology, Shanghai Skin Disease Hospital, Skin Disease Hospital of Tongji University, Shanghai 200050, China

Received:2022-10-12 Revised:2023-01-06 Published:2023-03-31
Contact: Qian Qiufang E-mail:qianqf@shchildren.com.cn

摘要/Abstract

摘要： 【摘要】报道2例Iso-Kikuchi综合征，均为先天性发病。例1女，7个月，因左手食指甲板异常7个月就诊；例2男，3岁，因左手食指甲板异常3年余就诊。2例均表现为左手食指中央无正常甲板，甲床两侧各有1个微小、独立的甲板。结合临床特点，2例均诊断为Iso-Kikuchi综合征。本文例1母亲孕期有使用黄体酮保胎史，2例患儿母亲孕期均因甲状腺功能减退症持续服用甲状腺激素治疗，且例2的母亲有妊娠期糖尿病病史。尚不能明确这些疾病和药物是否与Iso-Kikuchi综合征有直接关系。

关键词: 先天性食指发育不良, Iso-Kikuchi综合征, 临床表现

Abstract: 【Abstract】 To report 2 cases of Iso-Kikuchi syndrome, both of which were congenital. Case 1, a 7-month-old female infant, visited the hospital due to abnormalities in the nail plate of the left index finger for 7 months; case 2, a 3-year-old male child, also visited the hospital due to abnormalities in the nail plate of the left index finger for 3 years. The 2 patients both presented with 2 tiny, independent nail plates on both sides of the nail bed of the left index finger, instead of normal nail plates. Based on their clinical features, the 2 patients were diagnosed with Iso-Kikuchi syndrome （congenital onychodysplasia of the index finger）. The mother of case 1 had a history of progesterone use to prevent miscarriage during pregnancy, the mothers of the two patients both suffered from hypothyroidism and continued to receive thyroid hormone replacement therapy during pregnancy, and the mother of case 2 had a history of gestational diabetes. It is still unclear whether these comorbidities and drugs are directly related to the occurrence of Iso-Kikuchi syndrome.

Key words: Congenital onychodysplasia of the index fingers, Iso-Kikuchi syndrome, Clinical manifestations

郑冰洁林晓陈佳钱秋芳. [开放获取] Iso-Kikuchi综合征2例[J]. 中华皮肤科杂志, 2023,56(4):313-315. doi:10.35541/cjd.20220719

Zheng Bingjie, Lin Xiao, Chen Jia, Qian Qiufang. Iso-Kikuchi syndrome: report of two cases[J]. Chinese Journal of Dermatology, 2023, 56(4): 313-315.doi:10.35541/cjd.20220719

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[开放获取] Iso-Kikuchi综合征2例

Iso-Kikuchi syndrome: report of two cases

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