中华皮肤科杂志 ›› 2023, Vol. 56 ›› Issue (1): 82-85.doi: 10.35541/cjd.20200586

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结缔组织痣的临床分型及组织病理研究进展

王逸飞    宋昊    缪秋菊    徐秀莲    孙建方   

  1. 中国医学科学院、北京协和医学院皮肤病医院病理科,南京  210042
  • 收稿日期:2020-06-12 修回日期:2021-03-24 发布日期:2023-01-03
  • 通讯作者: 徐秀莲;孙建方 E-mail:xxlqjl@sina.com; sunjf57@163.com
  • 基金资助:
    中央高校基本科研业务费专项资金(3332019103)

Clinical classification and histopathological features of connective tissue nevi

Wang Yifei, Song Hao, Miao Qiuju, Xu Xiulian, Sun Jianfang   

  1. Department of Pathology, Hospital of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing 210042, China
  • Received:2020-06-12 Revised:2021-03-24 Published:2023-01-03
  • Contact: Xu Xiulian; Sun Jianfang E-mail:xxlqjl@sina.com; sunjf57@163.com
  • Supported by:
    The Fundamental Research Funds for the Central Universities(3332019103)

摘要: 【摘要】 结缔组织痣(CTN)是一种良性皮肤错构瘤,依据病变的主要构成组分分为胶原蛋白型、弹性蛋白型和蛋白多糖型三大类,各类又包含多种遗传性及获得性疾病,因此需结合遗传信息、临床表现和组织病理学特征确诊CTN及其具体亚型。本文依据国内外最新文献,将CTN的临床分型及组织病理学进展进行详尽地整理综述,以期进一步加强对此病的认识理解。

关键词: 错构瘤, 国际疾病分类法, 病理过程, 结缔组织痣

Abstract: 【Abstract】 Connective tissue nevi (CTN), a kind of benign skin hamartomas, can be classified into 3 types according to the excessive components predominating in skin lesions, including collagen type, elastin type and proteoglycan type, and each type of CTN includes various inherited and acquired diseases. Therefore, genetic, clinical, and histopathological features should be considered for confirmed diagnosis of CTN subtypes. According to the latest Chinese and international literature, this review elaborates clinical classification and histopathological characteristics of CTN, aiming to further strengthen the understanding of this disease.

Key words: Hamartoma, International classification of diseases, Pathologic processes, Connective tissue nevi