中华皮肤科杂志 ›› 2020, Vol. 53 ›› Issue (7): 569-572.doi: 10.35541/cjd.20190804

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血管瘤与脉管畸形分类进展

李丽,马琳   

  1. 国家儿童医学中心 首都医科大学附属北京儿童医院皮肤科 100045
  • 收稿日期:2019-08-06 修回日期:2020-05-22 发布日期:2020-07-06
  • 通讯作者: 马琳 E-mail:bch_maleen@aliyun.com
  • 基金资助:
    北京市医院管理中心儿科学科协同发展中心专项

Classification of hemangiomas and vascular malformations

Li Li,Ma Lin   

  1. Department of Dermatology, Beijing Children′s Hospital, Capital Medical University, National Center for Children′s Health, Beijing 100045, China
  • Received:2019-08-06 Revised:2020-05-22 Published:2020-07-06
  • Contact: Ma Lin E-mail:bch_maleen@aliyun.com
  • Supported by:
    Special Fund of the Pediatric Medical Coordinated Development Center of Beijing Hospitals Authority

摘要: 【摘要】 血管瘤和脉管畸形从最原始的形态学分类到现在的生物学特性分类历经数百年的历史。2018年国际血管异常研究会(ISSVA)在1996版、2014版分类基础上,对血管肿瘤进行细化及补充,增添了15种少见的血管肿瘤;脉管畸形中,对毛细血管畸形亚型进行重新分类,将“疣状血管瘤”更名为“疣状血管畸形”,增添了“肢体毛细血管畸形合并先天性非进展性肢体过度发育” 、“CLAPO综合征”等疾病,并增加了PIK3CA相关的过度增殖性疾病谱这一类疾病。本文阐述血管瘤与脉管畸形的分类萌芽、传统分类及现代分类,比较1996版、2014版及2018版ISSVA分类的异同,并阐述血管瘤与脉管畸形的现代分类对诊断和治疗的意义。

关键词: 血管瘤, 血管畸形, 淋巴管畸形, 诊断, 分类法

Abstract: 【Abstract】 Classification of hemangiomas and vascular malformations has gone through centuries of history from the most primitive morphological classification to the current biological classification. In 2018, the International Society for the Study of Vascular Abnormalities (ISSVA) refined and supplemented the classification of vascular tumors based on the 1996 and 2014 editions, and added 15 rare vascular tumors; for vascular malformations, the 2018 ISSVA classification reclassified the subtypes of capillary malformations, renamed "verrucous hemangioma" as "verrucous vascular malformation", added "limb capillary malformation with congenital non-progressive limb overgrowth", "CLAPO syndrome", PIK3CA-related hyperproliferative diseases, and so on. This review elaborates the primitive classification, traditional classification and modern classification of hemangiomas and vascular malformations, compares the similarities and differences among the 1996, 2014 and 2018 ISSVA classifications, and discusses the significance of the modern classification of hemangioma and vascular malformations for diagnosis and treatment.

Key words: Hemangioma, Vascular malformations, Lymphatic malformation, Diagnosis, Classification

引用本文

李丽 马琳. 血管瘤与脉管畸形分类进展[J]. 中华皮肤科杂志, 2020,53(7):569-572. doi:10.35541/cjd.20190804

Li Li Ma Lin. Classification of hemangiomas and vascular malformations[J]. Chinese Journal of Dermatology, 2020, 53(7): 569-572.doi:10.35541/cjd.20190804