中华皮肤科杂志 ›› 1983, Vol. 16 ›› Issue (4): 236-238.

• 论著 • 上一篇    下一篇

SLE精神神经障碍46例临床分析

许德清1, 高亚东1, 岑桂芹1, 赵耕源2   

  1. 1. 中山医学院第二附属医院皮肤科;
    2. 中山医学院第二附属医院神经科
  • 出版日期:1983-12-15 发布日期:1983-12-15

A clinical analysis of 46 cases of SLE with neuropsychiatric disturbance

Xu Deqin1   

  • Online:1983-12-15 Published:1983-12-15

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摘要： 本文对46例伴有精神神经障碍的SLE患者作了分析和讨论.在本组患者中精神障碍21例(45.7%).神经损害25例(54.3%).对精神障碍、颅内高压症、蛛网膜下腔出血、颅神经或周围神经损害和震颤性麻痹综普症等用大一剂量激素(强的松80-135mg/天)治疗效果较好.激素合并硫唑嘌呤较单用为好-本组病例随访到980年6月.存活21例,死亡25例.5年存活率为28.2%预后比肾损害者更惑亡原由有神经系统损鲁苯身、其它临床症状和并发愚染,每类型约各占1/3.

Abstract: Fortx-six cases of, SLE with neuropsychiatric disturbance were analysed and discussed, Among themo 21 cases (45.7%) were with psychiatric symptoms, and 25 cases(54.3%)with neurological involvement.Those cases with psychiatric disturbance, intracranial hypertension, subarachnoid haemorrhage, cranial or peripheral A-neuropathy and Parkinsori's syndrome gave favourable response to steroid therapy in high dosage, for example, 80-135 mg of prednisone per dap. The result of steroid plus azathioprine therappy was better than that of steroid alone.