中华皮肤科杂志 ›› 1982, Vol. 15 ›› Issue (2): 72-74.

• 论著 • 上一篇    下一篇

cANBP与银屑病

刘忠环1, 黄苏1, 宋芳吉1, 张恩涛2   

  1. 1. 中国医科大学第一医院皮肤科;
    2. 中国医科大学同位素教研室
  • 出版日期:1982-06-15 发布日期:1982-06-15

cAMP and Psoriasis

Liu Zhonghuan1   

  • Online:1982-06-15 Published:1982-06-15

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摘要： 本文采用竞争性蛋白质结合分析法测定了22例银屑病:患者受累与未受累皮肤的cAMP水平.同时应用了两种改进的皮肤切片技术:一是在样品中包括全部表皮和真皮,二是同时切取受累与未受累的皮肤样品,以避免由于缺血(Ischemic)作用而引起的人为差异.结果表明受累皮肤的CAMP水平明显低于未受累皮肤的CAMP水平.银屑病是与CAMP缺乏有关的.

Abstract: The cAMP levels in involved and uninvolved skin of 22 Psoriatic patients were determined by protein binding method. Two improvements is skin biopsy techniques were made; (1)including all epidermis and dermis in the sainpies; (2)moving the samples of involved and uninvolved skin at the same time to avoid any artificial changes due to ischemic effect, The result showed. that the cAMP level in inyolved skin was significantly lower than that in uninvolved skin, The authors considered that psoriasis was related to the cAMP deficiency.