中华皮肤科杂志 ›› 1981, Vol. 14 ›› Issue (3): 129-131.

• 论著 •    下一篇

口服川白芷制剂加黑光照射治疗银屑病159例疗效观察

重庆市银肩病防治研究协作组   

  1. 重庆市银肩病防治研究协作组
  • 出版日期:1981-09-15 发布日期:1981-09-15

Treatment of Psoriasis with Oral Preparations of Chuan Bai Zhi and Black Light：A Report of Therapeutic Effect in 159 Patients

Chongqing Cooperative Psoriasis Research Group   

  • Online:1981-09-15 Published:1981-09-15

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摘要： 1976年以来,我市皮肤科工作者开始探时用中药加黑光照射疗法治疗银屑病①.经动物实验和临床使用,筛选出川白芷、牛尾独活、补骨脂、虎杖等有效药物②③.近年来,在各协作单位共同努力下,不断改进剂型,至1979年8月底已用口服川白芷制剂加黑光照射治疗银屑病159例,取得良好疗效,兹报告如下.

Abstract: Chuan Bai Zhi(Angelicae dahuricae var, Tawainiana)is a commonly used Chinese traditional medicinal herb.159 psoriatics reluctant to various modalities of therapy were treated with oral preparations of Chuan Bai Zhi(CBZ)plus black light with favourable therapeutic results.These patients were given CBZ-1 10g or CBZ-3, CBZ-4, CBZ-5 4-6 capsules by mouth, and two hours ater, they were exposed to black.light with a dose of 1.5-4.0 J/cm2,3 to 6 times a week.Among these 159 patients, the final results were 76(47.2%)fully recovered(lesions completely disappeared),36(22.0%)almost recovered(more than 90 percent of lesions disappeared),33(20.8%)had evident improvement (more than 70 percent of lesions disappeared),7(4.4%)improvement(more than 50 percent of lesions disappeared)and in 9 patients(5.6%)the result was unsatisfactory(less than 50, percent of lesions disappeared).Side-effects of the therapy were fairly xriild,manifested as trasient dizziness,nausea,discomfort of stomach,itching etc.Further treatments were not interrupted.Functional tests of liver and kidney,and routine tests of blood and urine of the patients showed no abnormalities.CBZ-3 was similar to 8-MOP in curative effect,but the side-effects of CB2-3 were milder than that of 8-MOP.The authors suggest that CBZ-3 is a valuable, preparation for treating psoriasis.