中华皮肤科杂志 ›› 1981, Vol. 14 ›› Issue (2): 75-79.

• 论著 • 上一篇    下一篇

耐讽类药麻风的临床和实验研究

李文忠1, 叶干运1, 王荷英1, 叶顺章1, 吴勤学1, 马林1, 张永发2, 马步宽2   

  1. 1. 中国医学科学院皮肤病研究所;
    2. 县漆湖医院
  • 出版日期:1981-06-15 发布日期:1981-06-15

Clinical and Experimental Studies on Sulfone Resistant Leprosy

Li Wenzhong1, Ye GanYun1, Wang Heying1, Ye Shunzhang1, Wu Qinxue1, Ma Lin1, Zhang Yongfa2, Ma Bukuan2   

  1. 1. Institute of Dermatology, Chinese Academy of Medical Sciences;
    2. Qinhu Leprosarium, Tai County, Jiangsu Province
  • Online:1981-06-15 Published:1981-06-15

摘要: 瘤型麻风应用枫类药治疗产生耐药性己被确急日益引起人们的重视,是麻风防治工作中的一个难题①.目前从世界各地已分离出几百株耐枫类药麻风菌株,由于耐矾类药物而复发的病例也日益增多.

Abstract: The most solid foundation for leprosy control today rests on the effectiveness of sulfone therapy.However,the emergence of dapsone resistance with increasing frequency raises a serious problem for program mes of treatment and control of leprosy.Twelve cases of dapsone resistant leprosy were proved by clinical trials and/or foot-pad tests of mice in Qinhu Leprosarium during the period of 1975 to 1979.