中华皮肤科杂志 ›› 1996, Vol. 29 ›› Issue (4): 323-233.

• 论著 • 上一篇    下一篇

皮肤神经鞘粘液瘤

范钦和1, Alen P. W.2   

  1. 1. 江苏省人民医院病理科 南京 210029;
    2. 澳大利亚南澳州伊丽莎白女皇医院病理科
  • 收稿日期:1995-08-05 修回日期:1995-11-24 出版日期:1996-08-15 发布日期:1996-08-15

Dermal Nerve Myxoma

Fan Qinhe1, Alen PW2   

  1. Department of Pathology, Jiangsu Province Hospital, Nanjing 210029
  • Received:1995-08-05 Revised:1995-11-24 Online:1996-08-15 Published:1996-08-15

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摘要： 皮肤神经鞘粘液瘤是近年来提出的较少见的良性软组织肿瘤.为了探讨该病的病变特点,我们报告18例并进行组织病理学、免疫组织化学观察及临床随访.结果示本病主要见于青少年,皮损常位于上肢和面部.组织病理学为一位于真皮和皮下的多结节状粘液性病变,丰富的粘液背景上分布梭形和星形的肿瘤细胞,似神经的环层小体.绝大部分病例S100蛋白为强阳性,支持其为神经鞘起源.有随访结果者无一复发.我们认为本病是一具有特征性病理变化的皮肤神经源性肿瘤,在一系列的命名中,我们认为以神经鞘粘液瘤为佳,能较准确地概括其主要病理变化.该病呈良性经过,局部手术切除即可获较好的治疗效果.

关键词: 神经鞘粘液瘤

Abstract: In order to study nerve sheath myxoma,arecently described rare soft tisue tumor,the lesions of eighteen cases of this disease have beenexamined by ligh tmicroscopy and immunohis-tochemical methods.The lesion ocured usually inteenagers.It tended to ocur in the upper limbs and faces.Light microscopicaly,the lobulated tumor was composed of spindle and stelate tumor cells in the abundant myxoid matrix,which looked like Pacinian corpuscles.S-100 protein immunohis-tochemistry was done in ten cases and demonstrated strongly positive in nine patients,further supporting this disease is originated from nerve sheath.A few nomenclatures have benn used for the identical lesions.The name dermal nerve sheath myxoma and neurothekeom a are recommended.

Key words: Dermal nerve sheath myxoma